Linking subjective cognitive decline to glymphatic dysfunction in Parkinson's disease

Glymphatic dysfunction is evident during the SCD stage in PD, fully accounting for the statistical association between sleep disturbances and memory performance. This finding highlights glymphatic impairment as a potential neurobiological correlate of cognitive status in PD.

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Publication Details

Journal
Neurobiology of Disease
Published
2026-03-05
DOI
https://doi.org/10.1016/j.nbd.2026.107344
Primary Topic
Cerebrospinal fluid and hydrocephalus
Type
article
Field-Weighted Citation Impact
0.00
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article

Linking subjective cognitive decline to glymphatic dysfunction in Parkinson's disease

Leikun Wang, Kefei Chen, Liujia Lu, Feng Wang et al.
Neurobiology of Disease
Cerebrospinal fluid and hydrocephalus
article

Linking subjective cognitive decline to glymphatic dysfunction in Parkinson's disease

Leikun Wang, Kefei Chen, Liujia Lu, Feng Wang, Qin Wen, Yao Lu, Feng Wang, Yi Ji, Kaidong Chen, Ruixuan Zhang, Li I. Zhang
article en

Abstract

Glymphatic dysfunction is evident during the SCD stage in PD, fully accounting for the statistical association between sleep disturbances and memory performance. This finding highlights glymphatic impairment as a potential neurobiological correlate of cognitive status in PD.

Neurobiology of DiseaseVol. 221
Wuxi People's Hospital (CN)
Reduced inequalities
Openalex Percentile: Top 34%
Cerebrospinal fluid and hydrocephalus
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