Retinal and Choroidal Changes in Neurofibromatosis Type 1 in Relation to Diagnostic Criteria and Disease Severity

NIR is more sensitive than OCTA for detecting choroidal abnormalities, whereas OCTA provides complementary quantitative insights. Reduced SFCT confirms choroidal involvement in NF1, and higher SCP metrics may reflect early remodeling or endothelial dysregulation. Larger, longitudinal studies are needed to validate DCP changes as potential markers of disease burden.

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Publication Details

Journal
Current Eye Research
Published
2026-03-04
DOI
https://doi.org/10.1080/02713683.2025.2611844
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
0.00
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OCT
article

Retinal and Choroidal Changes in Neurofibromatosis Type 1 in Relation to Diagnostic Criteria and Disease Severity

Figen Bezci Aygün, Sibel Öz Yıldız, Sibel Kadayıfçılar, Burçak Karaca et al.
Current Eye Research
Neurofibromatosis and Schwannoma Cases
article

Retinal and Choroidal Changes in Neurofibromatosis Type 1 in Relation to Diagnostic Criteria and Disease Severity

Figen Bezci Aygün, Sibel Öz Yıldız, Sibel Kadayıfçılar, Burçak Karaca, Göknur Haliloğlu, Merve Özge Algedik Tokyürek, Yasemin Kapucu Yatağanbaba, Rahşan Göçmen
article en

Abstract

NIR is more sensitive than OCTA for detecting choroidal abnormalities, whereas OCTA provides complementary quantitative insights. Reduced SFCT confirms choroidal involvement in NF1, and higher SCP metrics may reflect early remodeling or endothelial dysregulation. Larger, longitudinal studies are needed to validate DCP changes as potential markers of disease burden.

Current Eye Research
Hacettepe University (TR)
Good health and well-being
Openalex Percentile: Top 40%
Neurofibromatosis and Schwannoma Cases
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