Genotype–Phenotype Correlation of Hereditary Plasminogen Deficiency: Molecular Mechanisms From 18 Patients With Cerebral Infarction

Patients with hereditary PLG deficiency resulting from PLG gene variants are at a significantly increased risk of CI, potentially attributable to diminished PLG catalytic activity and consequent impairment of fibrinolytic function.

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Publication Details

Journal
Haemophilia
Published
2026-03-04
DOI
https://doi.org/10.1111/hae.70248
Primary Topic
Protease and Inhibitor Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Genotype–Phenotype Correlation of Hereditary Plasminogen Deficiency: Molecular Mechanisms From 18 Patients With Cerebral Infarction

Yanhui Jin, Dandan Yu, Haixiao Xie, L L Yang et al.
Haemophilia
Protease and Inhibitor Mechanisms
article

Genotype–Phenotype Correlation of Hereditary Plasminogen Deficiency: Molecular Mechanisms From 18 Patients With Cerebral Infarction

Yanhui Jin, Dandan Yu, Haixiao Xie, L L Yang, Fei Xu, Yifan Lu
article en

Abstract

Patients with hereditary PLG deficiency resulting from PLG gene variants are at a significantly increased risk of CI, potentially attributable to diminished PLG catalytic activity and consequent impairment of fibrinolytic function.

Haemophilia
Wenzhou Medical University (CN), First Affiliated Hospital of Wenzhou Medical University (CN)
Zero hunger
Openalex Percentile: Top 33%
Protease and Inhibitor Mechanisms
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