Red Blood Cell Metabolomic Signatures in β-Thalassemia Heterozygotes With Elevated HbA <sub>1c</sub> : Implications for Biomarkers and Personalized Medicine
Distinct RBC metabolic signatures were observed in BTHs with elevated HbA<sub>1c</sub>, highlighting alterations in redox and heme metabolism. These findings provide a basis for future investigations into RBC-derived metabolites as complementary tools for glycemic assessment in individuals with thalassemia and hemoglobinopathies.
Authors
- Orawan Sarakul (ORCID: https://orcid.org/0000-0003-0826-197X)
- Manit Nuinoon (ORCID: https://orcid.org/0000-0002-1325-5489)
- Duangjai Piwkham
- Nutjaree Jeenduang (ORCID: https://orcid.org/0000-0002-1597-5666)
- Wiphaphon Khongsathan
Institutions
- Nakhon Si Thammarat Rajabhat University (TH)
- Walailak University (TH)
Publication Details
- Journal
- Journal of Diabetes Science and Technology
- Published
- 2026-03-03
- DOI
- https://doi.org/10.1177/19322968261426026
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Thailand Science Research and Innovation