The APOE paradox: divergent genetic influences on hemorrhagic stroke risk—A meta-analysis
Our findings suggest that APOE ε2/ε2, ε2/ε4, ε2, and ε4/ε4 genotypes and the ε4 allele are associated with an elevated risk of HS. These results highlight the potential role of APOE genotypes in HS susceptibility and warrant further investigation.
Authors
- Manabesh Nath (ORCID: https://orcid.org/0000-0001-5979-8377)
- Shubham Misra (ORCID: https://orcid.org/0000-0002-4920-2573)
- Pradeep Kumar
- Astha Rai
Institutions
- Yale University (US)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Frontiers in Stroke
- Published
- 2026-03-04
- DOI
- https://doi.org/10.3389/fstro.2026.1684121
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00