Ameliorative effects of desert truffle Terfezia claveryi extract on Hysterothylacium thalassini- induced oxidative damage in C57BL/6 mice

<i>T. claveryi</i> extract exhibits potent antioxidant and immunomodulatory effects that mitigate oxidative damage and inflammatory stress induced by <i>H. thalassini</i> infection in mice. Although the extract does not target the parasite burden directly, its ability to restore oxidant-antioxidant balance and modulate host immune responses suggests a valuable supportive or adjunctive role in reducing infection-associated tissue injury and immunopathology. These findings indicate that desert truffle-derived bioactive compounds may serve as natural complementary agents to limit oxidative and inflammatory complications associated with anisakid infections and warrant further investigation in combination with antiparasitic therapies.