Impaired mucosal IgA response to SARS-CoV-2 in patients with inborn errors of immunity

These findings underscore the critical role of mucosal IgA in protection and highlight persistent vulnerability in PAD patients despite IgG replacement therapy.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-03-04
DOI
https://doi.org/10.3389/fimmu.2026.1696834
Primary Topic
Immunodeficiency and Autoimmune Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Impaired mucosal IgA response to SARS-CoV-2 in patients with inborn errors of immunity

Samaneh Delavari, Sara Iranparast, F Abolnezhadian, Fereshte Salami et al.
Frontiers in Immunology
Immunodeficiency and Autoimmune Disorders
article

Impaired mucosal IgA response to SARS-CoV-2 in patients with inborn errors of immunity

Samaneh Delavari, Sara Iranparast, F Abolnezhadian, Fereshte Salami, Samin Sharafian, Sima Shokri, Hassan Abolhassani, Nima Rezaei, Yating Wang, Fanglei Zuo
article en

Abstract

These findings underscore the critical role of mucosal IgA in protection and highlight persistent vulnerability in PAD patients despite IgG replacement therapy.

Frontiers in ImmunologyVol. 17
Ahvaz Jundishapur University of Medical Sciences (IR), Karolinska Institutet (SE), Rasool Akram Hospital (IR), Shahid Beheshti University of Medical Sciences (IR), Tehran University of Medical Sciences (IR)
Petrus och Augusta Hedlunds Stiftelse, Magnus Bergvalls Stiftelse, Stiftelsen Clas Groschinskys Minnesfond
Good health and well-being
Openalex Percentile: Top 34%
Immunodeficiency and Autoimmune Disorders
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