Cytokine imbalance and HBV-specific T-cell exhaustion predict disease progression in HIV-HBV coinfection

HIV-HBV coinfection was characterized by HBV reactivation, cytokine imbalance, and T-cell exhaustion, which were associated with disease progression and may inform risk stratification.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-03-04
DOI
https://doi.org/10.3389/fimmu.2026.1789692
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Cytokine imbalance and HBV-specific T-cell exhaustion predict disease progression in HIV-HBV coinfection

Peter Asaga Mac, Mansur Aliyu Ramalan, Bako A. Ishaku, Dave C. Ibeh
Frontiers in Immunology
Hepatitis B Virus Studies
article

Cytokine imbalance and HBV-specific T-cell exhaustion predict disease progression in HIV-HBV coinfection

Peter Asaga Mac, Mansur Aliyu Ramalan, Bako A. Ishaku, Dave C. Ibeh
article en

Abstract

HIV-HBV coinfection was characterized by HBV reactivation, cytokine imbalance, and T-cell exhaustion, which were associated with disease progression and may inform risk stratification.

Frontiers in ImmunologyVol. 17
Federal University Lafia (NG), Institute of Epidemiology, Disease Control and Research (BD), Army Hospital Research and Referral (IN)
World Health Organization
Good health and well-being
Openalex Percentile: Top 35%
Hepatitis B Virus Studies
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