Histopathological evaluation of local effects of radioactive iodine seeds in axillary lymph nodes in clinically node-positive breast cancer treated with neoadjuvant systemic therapy
Fibrosis, foamy histiocytes, and macrometastases were significantly more present in MARI compared to non-MARI nodes. Moreover, <sup>125</sup>I seed absorbed radiation dose had no significant effect on histopathologic features in MARI nodes.
Authors
- L. Kooreman
- Melissa Lenaerts (ORCID: https://orcid.org/0000-0001-9687-4375)
- Koppert Linetta B.
- Janine M. Simons (ORCID: https://orcid.org/0000-0002-1264-4693)
- L. Murrer
- Thiemo J A van Nijnatten
- Ernest J.T. Luiten
- Florien J.G. van Amstel
- S. M. J. van Kuijk
- Cornelis M. de Mooij
- Carmen C. van der Pol
- Paul J. van Diest
- Marjolein L. Smidt
Institutions
- Radboud University Nijmegen (NL)
- Maastricht University Medical Centre (NL)
- Radboud University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Maastricht University (NL)
- Medisch Centrum Haaglanden (NL)
- Alrijne Ziekenhuis (NL)
- Amphia Ziekenhuis (NL)
- Erasmus MC Cancer Institute (NL)
- Maastro Clinic (NL)
- Rotterdam University of Applied Sciences (NL)
Publication Details
- Journal
- The Breast
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1016/j.breast.2026.104746
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00