Spectrum of Primary Aldosteronism and Risk of Cardiovascular Outcomes
The findings of this cohort study underscore a spectrum of primary aldosteronism, in which higher ARR was independently associated with increased risks of AF and ischemic stroke among older adults, supporting the aldosterone pathway as a potential target for CVD prevention.
Authors
- Jeremy Van’t Hof (ORCID: https://orcid.org/0000-0002-9982-3685)
- John W. Ostrominski (ORCID: https://orcid.org/0000-0002-2866-9414)
- Mats Christian Højbjerg Lassen (ORCID: https://orcid.org/0000-0002-2255-582X)
- Amil M. Shah (ORCID: https://orcid.org/0000-0003-1056-4451)
- J Y Lee
- Jenifer M. Brown (ORCID: https://orcid.org/0000-0002-6647-639X)
- Magnus Wijkman (ORCID: https://orcid.org/0000-0002-4757-9051)
- S D Solomon
- Brian L. Claggett
- Muthiah Vaduganathan
- Tor Biering-Sørensen
Institutions
- Linköping University (SE)
- University of North Carolina at Chapel Hill (US)
- University of Copenhagen (DK)
- Brigham and Women's Hospital (US)
- University of Minnesota (US)
- Gentofte Hospital (DK)
- Minneapolis Heart Institute Foundation (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- JAMA Cardiology
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1001/jamacardio.2026.0068
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 0.00