Finding the optimal recall rate in breast cancer screening: results from the ROCS study

Question Breast cancer screening requires a good balance between detection and false-positive rate. However, the interrelationship between these rates, and thus the optimal recall, is unknown. Findings Overall, the Dutch screening radiologists performed with high accuracy, and the current operating point optimizes the trade-off between cancer detection and false-positive recalls. Clinical relevance ROCS provides an efficient method to evaluate performance and determine target values based on data from screening practice. This method applies to various screening programs. Screening evaluation is essential for achieving and maintaining a positive benefit-to-harm ratio for participants.