Chidamide combined with fulvestrant in the treatment of HR-positive, HER2-negative advanced breast cancer after failure of previous endocrine therapy: a single-arm, single-center, phase 2 study

Chidamide combined with fulvestrant showed encouraging antitumor activity and tolerable toxicity in pts with HR + /HER2- advanced breast cancer that had progressed after previous endocrine therapy. Trial registration ChiCTR2100044282, registered on March 14th 2021.

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Publication Details

Journal
Breast Cancer Research
Published
2026-03-04
DOI
https://doi.org/10.1186/s13058-026-02254-3
Primary Topic
Advanced Breast Cancer Therapies
Type
article
Field-Weighted Citation Impact
0.00
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article

Chidamide combined with fulvestrant in the treatment of HR-positive, HER2-negative advanced breast cancer after failure of previous endocrine therapy: a single-arm, single-center, phase 2 study

La Zou, L. Q. Yang, X. Tan, T. Yang et al.
Breast Cancer Research
Advanced Breast Cancer Therapies
article

Chidamide combined with fulvestrant in the treatment of HR-positive, HER2-negative advanced breast cancer after failure of previous endocrine therapy: a single-arm, single-center, phase 2 study

La Zou, L. Q. Yang, X. Tan, T. Yang, Y. Liu, P. Deng, W. Li, Xianjun Tang, Xiaohua Zeng
article en

Abstract

Chidamide combined with fulvestrant showed encouraging antitumor activity and tolerable toxicity in pts with HR + /HER2- advanced breast cancer that had progressed after previous endocrine therapy. Trial registration ChiCTR2100044282, registered on March 14th 2021.

Breast Cancer Research
Chongqing University (CN), Chongqing Cancer Hospital (CN)
Good health and well-being
Openalex Percentile: Top 34%
Advanced Breast Cancer Therapies
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