Autonomous AI-assisted diabetic retinopathy screening at primary care is associated with increased presentation to eye care by at risk patients

Adult patients with diabetes (n = 3745) seen at Johns Hopkins Medicine primary care sites were referred to the Wilmer Eye Institute either based on a primary care provider referral or autonomous AI diagnostic result (referral was made after a positive or non-diagnostic result). An inverse-probability-weighted regression, which incorporated propensity score matching on social determinants of health and relevant clinical variables, showed that implementation of an autonomous AI-assisted diabetic screening program in a primary care clinic was associated with increased presentation to eye care specialist care by African-Americans (p = 0.02). This is significant because African-Americans have traditionally been less likely to undergo annual screening exams and more likely to present with more severe forms of diabetic retinopathy (DR). The results suggest a potential association between office-based, AI-assisted DR screening and improved downstream ophthalmic access for African-American patients. However, given that the analysis was exploratory, this association should be interpreted cautiously and further validated.

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Publication Details

Journal
npj Digital Medicine
Published
2026-03-05
DOI
https://doi.org/10.1038/s41746-026-02460-5
Primary Topic
Retinal Imaging and Analysis
Type
article
Field-Weighted Citation Impact
0.00

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article

Autonomous AI-assisted diabetic retinopathy screening at primary care is associated with increased presentation to eye care by at risk patients

Ariel K. Leong, RISA M. WOLF, Jiangxia Wang, T. Y. Alvin Liu et al.
npj Digital Medicine
Retinal Imaging and Analysis
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Autonomous AI-assisted diabetic retinopathy screening at primary care is associated with increased presentation to eye care by at risk patients

Ariel K. Leong, RISA M. WOLF, Jiangxia Wang, T. Y. Alvin Liu, Harold Lehmann, Michael D. Abramoff, Roomasa Channa
article en

Abstract

Adult patients with diabetes (n = 3745) seen at Johns Hopkins Medicine primary care sites were referred to the Wilmer Eye Institute either based on a primary care provider referral or autonomous AI diagnostic result (referral was made after a positive or non-diagnostic result). An inverse-probability-weighted regression, which incorporated propensity score matching on social determinants of health and relevant clinical variables, showed that implementation of an autonomous AI-assisted diabetic screening program in a primary care clinic was associated with increased presentation to eye care specialist care by African-Americans (p = 0.02). This is significant because African-Americans have traditionally been less likely to undergo annual screening exams and more likely to present with more severe forms of diabetic retinopathy (DR). The results suggest a potential association between office-based, AI-assisted DR screening and improved downstream ophthalmic access for African-American patients. However, given that the analysis was exploratory, this association should be interpreted cautiously and further validated.

npj Digital Medicine
University of Iowa (US), University of Wisconsin–Madison (US), Johns Hopkins University (US), Johns Hopkins Medicine (US)
Research to Prevent Blindness
Good health and well-being
Openalex Percentile: Top 36%
Retinal Imaging and Analysis
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