Impacts of host genetics on gut microbiome composition in Alzheimer’s disease

In summary, our study reveals the complex genetic effects on the gut microbiota in AD, and provides novel evidence for the roles of the gut-brain axis in AD. Video Abstract.

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Publication Details

Journal
Microbiome
Published
2026-03-05
DOI
https://doi.org/10.1186/s40168-026-02342-8
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Impacts of host genetics on gut microbiome composition in Alzheimer’s disease

Senying Lai, Longhao Jia, Jixin Cao, Anyi Yang et al.
Microbiome
Gut microbiota and health
article

Impacts of host genetics on gut microbiome composition in Alzheimer’s disease

Senying Lai, Longhao Jia, Jixin Cao, Anyi Yang, Xing-Ming Zhao, Yucheng T. Yang, Feng Chen, Jinxin Liu, Xingzhong Zhao, Ziquan Gan
article en

Abstract

In summary, our study reveals the complex genetic effects on the gut microbiota in AD, and provides novel evidence for the roles of the gut-brain axis in AD. Video Abstract.

Microbiome
Zhejiang Sci-Tech University (CN), Sun Yat-sen University (CN), Fudan University (CN), Shanghai Institute for Science of Science (CN), Huzhou Central Hospital (CN), Zhongshan Hospital (CN), Hainan General Hospital (CN), The First Affiliated Hospital, Sun Yat-sen University (CN), Obstetrics and Gynecology Hospital of Fudan University (CN), Shanghai Center for Brain Science and Brain-Inspired Technology (CN), Hainan Medical University (CN)
Zero hunger
Openalex Percentile: Top 34%
Gut microbiota and health
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