Sentinel lymph node biopsy versus lymphadenectomy in early-stage cervical cancer: a meta-analysis of oncologic outcomes and surgical morbidity
This study suggests that SLNB provides oncologic outcomes comparable to LND while reducing surgical morbidity in early-stage cervical cancer. The inclusion of CSS as a validated endpoint reinforces the cancer-specific safety of SLNB, with no significant compromise observed in either OS or PFS. While current evidence is promising, further large-scale prospective trials are needed to refine indications and standardize implementation of SLNB in routine clinical practice.
Authors
- Siyuan Zeng (ORCID: https://orcid.org/0000-0002-5924-9957)
- Ruiqi Wang
- Chao Xiao
- Xue Xiao
- Luying Li
Institutions
- Sichuan University (CN)
- West China Second University Hospital of Sichuan University (CN)
- Zigong First People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-03-04
- DOI
- https://doi.org/10.3389/fonc.2026.1765529
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China