Serum biomarkers for predicting Crohn’s disease activity: The role of bilirubin, uric acid, and the C-reactive protein/albumin ratio

Our findings support a potential serological remission hypothesis for Crohn's disease, characterized by a post-treatment rise in total bilirubin, together with a decrease in C-reactive protein to approximately 5.3 mg/L and the C-reactive protein/albumin ratio to about 0.136. This hypothesis warrants prospective validation.