A comparative dosimetric evaluation of two image-guided calibration strategies for multi-isocenter total body irradiation: integrated fan-beam CT–based alignment versus sequential cone-beam CT–guided localization
FBCT guidance gave better target dose conformity and homogeneity, and lower lung doses, than CBCT guidance-both for the 12 Gy myeloablative regimen and the 3 Gy low-dose regimen. These results suggest that FBCT guidance is a better option for image-guided total body irradiation in children.
Authors
- Xiwei Chen (ORCID: https://orcid.org/0000-0003-1868-8387)
- Zhanquan Lei
- Bo Gao (ORCID: https://orcid.org/0000-0003-3070-2962)
- Yi Yan (ORCID: https://orcid.org/0000-0003-2860-3252)
- Junjing Yan
- Lizhen Wu
- Zhaojie Yao
- Yaling Hong
- Suhua Tan
- Yutao Zhu
Institutions
- Fujian Medical University (CN)
- Fujian Women and Children Hospital (CN)
- Shanghai Children's Medical Center (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-03-04
- DOI
- https://doi.org/10.3389/fonc.2026.1760909
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Fujian Province