Association and Multimodal Model of Retinal Mid-Peripheral Capillary Free Zones with Structural and Functional Parameters in Diabetic Patients Without Clinical Retinopathy

These findings demonstrate that enlarged mid-peripheral periarteriole CFZs are associated with thinner RNFL in diabetics without clinical retinopathy. The multimodal model of vascular and structural metrics showed modestly improved diagnostic ability. This study shows early novel retinal vascular and neural associations in diabetics without clinical retinopathy and demonstrates the potential utility of a multimodal model for discriminating this group from healthy controls.