Health-related quality of life in children with multiple endocrine neoplasia (MEN) and their siblings
Overall, children with MEN reported HRQoL comparable to siblings and age-matched Dutch norms, except for reduced physical functioning in MEN2B. Clinical manifestations negatively affected physical, social, and school functioning, suggesting that children with onset of disease may benefit from closer monitoring and targeted psychosocial support.
Authors
- Theo Sas (ORCID: https://orcid.org/0000-0002-8727-1385)
- Saartje Straetemans (ORCID: https://orcid.org/0000-0001-7857-3608)
- A. A. Verrijn Stuart (ORCID: https://orcid.org/0000-0002-3999-8854)
- Hanneke M. van Santen (ORCID: https://orcid.org/0000-0002-6773-6931)
- Sasja A. Schepers (ORCID: https://orcid.org/0000-0001-9069-0874)
- H. L. Claahsen- van der Grinten
- Daniël Zwerus (ORCID: https://orcid.org/0000-0002-0545-8569)
- Christiaan de Bruin
- Christiaan F Mooij
- Rachel S van Leeuwaarde
- Gianni Bocca
- Gerlof D Valk
Institutions
- University Medical Center Groningen (NL)
- Maastricht University Medical Centre (NL)
- University Medical Center Utrecht (NL)
- Diabetes Care and Research Foundation (IN)
- Emma Kinderziekenhuis (NL)
- Amsterdam Neuroscience (NL)
- Amalia Kinderziekenhuis (NL)
- Diabetes Care Center (US)
- Beatrix Kinderziekenhuis (NL)
- Princess Máxima Center (NL)
- Willem-Alexander Kinderziekenhuis (NL)
- Erasmus MC - Sophia Children’s Hospital (NL)
- Amsterdam University Medical Centers (NL)
- Wilhelmina Children's Hospital (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2026-03-03
- DOI
- https://doi.org/10.1210/clinem/dgag094
- Citations
- 1
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 30.73