Beyond plasma: defining the translation value of epithelial lining fluid exposure profiles for the treatment of pneumonia
These data demonstrate the clinical translation of the pneumonia model relative to established breakpoints and emphasizes the potential limitations of relying solely on plasma exposure targets in predicting clinical efficacy for pneumonia.
Authors
- Yakun Fu (ORCID: https://orcid.org/0009-0008-9359-0930)
- Andrew J Fratoni (ORCID: https://orcid.org/0000-0002-5874-5174)
- David P Nicolau
Institutions
- Hartford Hospital (US)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2026-02-24
- DOI
- https://doi.org/10.1093/jac/dkaf458
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 0.00