Risk factors of histologic upgrade between colposcopy-directed biopsy and loop electrosurgical excision procedure in cervical squamous intraepithelial lesions: a retrospective study
Our study identified that HPV16/18 infection and a non-fully visible cervical transformation zone are significant risk factors associated with histologic upgrade between CDB and subsequent LEEP conization.
Authors
- Yuanbo Ling
- Yong Zhi
- Tingting Zhang (ORCID: https://orcid.org/0000-0003-1944-0738)
- Bowen Xu (ORCID: https://orcid.org/0009-0004-6968-0435)
- Liyan Sun
- Heling Ma
- Fang Li
- Jie Xu
- Yuan Ma
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai East Hospital (CN)
- Yueyang Hospital (CN)
- Pudong New Area People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-03-04
- DOI
- https://doi.org/10.3389/fmed.2026.1761098
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Science and Technology Development Foundation
- National Natural Science Foundation of China