Evaluating large language models for automated TNM staging from PET-CT reports: a multi-cancer comparative study

Among the three LLMs, ChatGPT 5 demonstrated the highest accuracy, stability, and efficiency in automated TNM staging from PET-CT reports, achieving performance comparable to or slightly exceeding junior radiologists. Its advantages in T staging and lung cancer evaluation highlight its clinical utility as a potential decision-support tool.

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Publication Details

Journal
Frontiers in Digital Health
Published
2026-03-04
DOI
https://doi.org/10.3389/fdgth.2026.1741973
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00

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article

Evaluating large language models for automated TNM staging from PET-CT reports: a multi-cancer comparative study

Qijun Shen, Wen Xu, Shushu Pan, Lixiu Cao et al.
Frontiers in Digital Health
Artificial Intelligence in Healthcare and Education
article

Evaluating large language models for automated TNM staging from PET-CT reports: a multi-cancer comparative study

Qijun Shen, Wen Xu, Shushu Pan, Lixiu Cao, Mei Ruan, Yanna Shan
article en

Abstract

Among the three LLMs, ChatGPT 5 demonstrated the highest accuracy, stability, and efficiency in automated TNM staging from PET-CT reports, achieving performance comparable to or slightly exceeding junior radiologists. Its advantages in T staging and lung cancer evaluation highlight its clinical utility as a potential decision-support tool.

Frontiers in Digital HealthVol. 8
Tangshan People's Hospital (CN), Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
Medical Science and Technology Project of Zhejiang Province, Science and Technology Program of Zhejiang Province
Quality Education
Openalex Percentile: Top 37%
Artificial Intelligence in Healthcare and Education
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