Integrating network pharmacology and experimental validation to elucidate the mechanism of Xiao-bi decoction in psoriasis treatment: Inhibition of JAK2/STAT3 signaling and rebalancing Th17/Treg responses
The herbal medicine Xiao-bi decoction may regulate the JAK2/STAT3 pathway, thereby influencing the Th17 response and Treg differentiation, and thereby alleviating the skin inflammation of psoriasis.
Authors
- Changhui Wen (ORCID: https://orcid.org/0000-0002-1702-0476)
- Xueying Zhang (ORCID: https://orcid.org/0000-0001-7674-0273)
- Guangfang Cheng
- Xiaoqiong Yang
- Haili Zhang
- Yan Fu
- Wencheng Chen
- Zidan Xiao
- Yue Han
- Jinqiang Zhang
Institutions
- Guiyang College of Traditional Chinese Medicine (CN)
- Guiyang Medical University (CN)
- Guizhou University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1016/j.jep.2026.121477
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00