Altered Expression of GABA-Related Genes in Schizophrenia: Insights from Meta-Analyses of Brain and Blood Samples and iPSC-Derived Organoids

Further studies are required to clarify the causal role of reduced GABAergic activity in schizophrenia pathogenesis and to evaluate the clinical relevance of <i>PVALB</i> expression for diagnosis and treatment monitoring.

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Publication Details

Journal
ALPHA PSYCHIATRY
Published
2026-02-25
DOI
https://doi.org/10.31083/ap43531
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Altered Expression of GABA-Related Genes in Schizophrenia: Insights from Meta-Analyses of Brain and Blood Samples and iPSC-Derived Organoids

Assif Yitzhaky, Libi Hertzberg, Yuval Singer
ALPHA PSYCHIATRY
Tryptophan and brain disorders
article

Altered Expression of GABA-Related Genes in Schizophrenia: Insights from Meta-Analyses of Brain and Blood Samples and iPSC-Derived Organoids

Assif Yitzhaky, Libi Hertzberg, Yuval Singer
article en

Abstract

Further studies are required to clarify the causal role of reduced GABAergic activity in schizophrenia pathogenesis and to evaluate the clinical relevance of <i>PVALB</i> expression for diagnosis and treatment monitoring.

ALPHA PSYCHIATRYVol. 27(1)
Tel Aviv University (IL), Shalvata Mental Health Center (IL), Weizmann Institute of Science (IL)
Openalex Percentile: Top 43%
Tryptophan and brain disorders
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