Increased secreted PLA2 in epithelial cells promotes the progression of chronic non-atrophic gastritis to chronic atrophic gastritis through the TGF-β signaling
Our study shows that PLA2G10 plays a key role in the progression of chronic gastritis and highlights the important role played by the TGF-β signalling pathway in this process.
Authors
- Hairong Hao
- Yingli Hao
- Yanjun An
- Junfeng Kang
- Yuan Liu
- Ran Zhang
- Na Li
- Baole Li
- Yuanyuan Pan
Institutions
- Xiyuan Hospital (CN)
- China Academy of Chinese Medical Sciences (CN)
- Shanxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1371/journal.pone.0343531
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00