Postdiagnostic Anxiety and Depression Increase Rupture Risk and Mortality in Unruptured Intracranial Aneurysms
Postdiagnostic anxiety and depression are associated with increased rupture risk and mortality in patients with unruptured intracranial aneurysms. Residual confounding cannot be excluded. These findings require further investigation to establish causality and suggest that an integrated psychiatric assessment may be considered in unruptured intracranial aneurysm management.
Authors
- N Haranhalli
- Mustafa S. Alhasan (ORCID: https://orcid.org/0009-0002-4401-5127)
- D Altschul
- Deepak Khatri (ORCID: https://orcid.org/0000-0003-1902-9623)
- Dhairya A. Lakhani (ORCID: https://orcid.org/0000-0001-7577-1887)
- Dheeraj Gandhi
- Ahmed Y. Azzam
- Muhammed Amir Essibayi
- Alireza Karandish
- Huanwen Chen
- Adam A. Dmytriw
Institutions
- West Virginia University (US)
- University of Maryland, Baltimore (US)
- Brigham and Women's Hospital (US)
- Albert Einstein College of Medicine (US)
- University of Maryland Medical Center (US)
- Montefiore Medical Center (US)
- The University of Texas MD Anderson Cancer Center (US)
- Johns Hopkins University (US)
- Taibah University (SA)
- Johns Hopkins Bayview Medical Center (US)
- Ontario Neurotrauma Foundation (CA)
- Blanchette Rockefeller Neurosciences Institute (US)
Publication Details
- Journal
- Stroke
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1161/strokeaha.126.054546
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00