Functional and structural retinal alterations in Alzheimer’s disease: insights from photopic negative response (PhNR) and OCT-based analysis
AD was associated with a generalized reduction in full-field ERG amplitudes, accompanied by selective retinal layer changes on OCT. Among electrophysiological measures, b-wave amplitude demonstrated the highest ability to distinguish AD patients from controls.
Authors
- Murat Gültekin
- Hatice Kubra Sonmez
- HİDAYET ŞENER
- Furkan Ozer
- Fatih Horozoglu
- Beyza Ogurlu
- Osman Ahmet Polat
Institutions
- Nevşehir Hacı Bektaş Veli University (TR)
- Erciyes University (TR)
Publication Details
- Journal
- Documenta Ophthalmologica
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1007/s10633-026-10089-8
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00