A genetic switch turns off parental behaviour and drives infanticide in male striped mice

Male parenting in mammals is highly variable, ranging from caring to neglectful and abusive. The brain and behaviour of the African striped mouse reveal that, in males, the social environment and expression level of the Agouti gene affect whether the animals will be hostile or caring towards pups. In striped mice, the social environment affects expression of the Agouti gene, which in turn can drive pup-directed hostility.

Publication Details

Journal
Nature
Published
2026-03-04
DOI
https://doi.org/10.1038/d41586-026-00656-z
Primary Topic
Neuroendocrine regulation and behavior
Type
article
Field-Weighted Citation Impact
0.00
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article

A genetic switch turns off parental behaviour and drives infanticide in male striped mice

Nature
Neuroendocrine regulation and behavior
article

A genetic switch turns off parental behaviour and drives infanticide in male striped mice

article en

Abstract

Male parenting in mammals is highly variable, ranging from caring to neglectful and abusive. The brain and behaviour of the African striped mouse reveal that, in males, the social environment and expression level of the Agouti gene affect whether the animals will be hostile or caring towards pups. In striped mice, the social environment affects expression of the Agouti gene, which in turn can drive pup-directed hostility.

Nature
Gender equality
Openalex Percentile: Top 44%
Neuroendocrine regulation and behavior
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A genetic switch turns off parental behaviour and drives infanticide in male striped mice · Nature (2026) | TGRS Research Map | TGRS