Correlation between anemia-related red blood cell parameters and pulmonary function severity in patients with AECOPD

Anemia is highly prevalent in AECOPD and is closely but moderately associated with disease severity. RDW and MCH are indicators that show independent associations with lung function impairment and selected clinical outcomes in this cohort, but these relationships cannot be interpreted as causal because of the observational study design. Integrating these readily available RBC parameters into routine assessment could help enhance risk stratification when interpreted alongside established clinical and physiological markers.