Lactobacillus acidophilus combined with Pediococcus acidilactici ameliorates colitis
The current study demonstrates that the combination of <i>Lactobacillus acidophilus</i> and <i>Pediococcus acidilactici</i> exerts protective effects against colitis in mice by the enhancement of antioxidant capacity, reduced inflammatory responses, preservation of intestinal barrier integrity, and partial restoration of gut microbiota and its metabolite production. Collectively, the study provides novel insights into the synergistic application of the specific probiotic pair for colitis management.
Authors
- Yi Jin (ORCID: https://orcid.org/0000-0003-1794-7017)
- Keesun Yu (ORCID: https://orcid.org/0000-0002-7596-1987)
- Lianhua Cui (ORCID: https://orcid.org/0000-0001-6866-6472)
- Young Jin Pyung (ORCID: https://orcid.org/0000-0001-8313-8475)
- Chong-Su Cho (ORCID: https://orcid.org/0000-0003-4671-700X)
- Mingzhu Wang (ORCID: https://orcid.org/0000-0003-1361-1540)
- Fuliang Sun
- Cheol-Heui Yun
- Da-Jeong Park
- Chunri Yan
- Xin Jin
- Peilin Yu
Institutions
- Seoul National University of Science and Technology (KR)
- Yanbian University of Science and Technology (CN)
- Yanbian University (CN)
- Biotechnology Research Institute (CA)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2026-03-04
- DOI
- https://doi.org/10.3389/fmicb.2026.1773197
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Department of Science and Technology of Jilin Province
- Higher Education Discipline Innovation Project
- Ministry of Science and ICT, South Korea