Use of cryobiopsy for diagnosis and treatment of a rarelaryngeal tumor in pediatrics

This report highlights the importance of differential diagnosis of laryngeal obstructive airway pathologies, as well as the growing value of endoscopic techniques, such as cryobiopsy, in achieving a definitive, accurate diagnosis. This is an 8-month-old infant who presented with signs of airway obstruction and a history consistent with foreign body aspiration. During endoscopy under general anesthesia, a supraglottic tumor was observed, which was resected using a cryobiopsy probe, a method that is not widely used in pediatrics and in our setting. Postoperative pathological anatomy confirmed the diagnosis of juvenile xanthogranuloma, a form of non-Langerhans cell histiocytosis with an uncommon location in the larynx.

Publication Details

Journal
Archivos Argentinos de Pediatria
Published
2026-03-04
DOI
https://doi.org/10.5546/aap.2025-10901.eng
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
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article

Use of cryobiopsy for diagnosis and treatment of a rarelaryngeal tumor in pediatrics

Archivos Argentinos de Pediatria
Head and Neck Cancer Studies
article

Use of cryobiopsy for diagnosis and treatment of a rarelaryngeal tumor in pediatrics

article en

Abstract

This report highlights the importance of differential diagnosis of laryngeal obstructive airway pathologies, as well as the growing value of endoscopic techniques, such as cryobiopsy, in achieving a definitive, accurate diagnosis. This is an 8-month-old infant who presented with signs of airway obstruction and a history consistent with foreign body aspiration. During endoscopy under general anesthesia, a supraglottic tumor was observed, which was resected using a cryobiopsy probe, a method that is not widely used in pediatrics and in our setting. Postoperative pathological anatomy confirmed the diagnosis of juvenile xanthogranuloma, a form of non-Langerhans cell histiocytosis with an uncommon location in the larynx.

Archivos Argentinos de PediatriaVol. 124(4)
Good health and well-being
Openalex Percentile: Top 33%
Head and Neck Cancer Studies
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Use of cryobiopsy for diagnosis and treatment of a rarelaryngeal tumor in pediatrics · Archivos Argentinos de Pediatria (2026) | TGRS Research Map | TGRS