Clinical feasibility of accelerated whole liver water T1 mapping with T2*-compensation
The developed water T1 (wT1) method enables broad liver coverage in a single 11-s breath-hold. Liver wT1 mapping and the proposed T2*-compensation (wT1<sub>comp</sub>) remove the bias in T1 induced by fat and iron, respectively. The analysis in all liver segments allows the assessment of focal liver changes. The proposed liver segments-based wT1<sub>comp</sub> method presents potential to identify tissue signal changes associated with fibrosis.
Authors
- Dimitrios C. Karampinos (ORCID: https://orcid.org/0000-0003-4922-3662)
- Jonathan Stelter (ORCID: https://orcid.org/0000-0003-3335-3331)
- Rolf Walter
- Mariya Doneva (ORCID: https://orcid.org/0000-0003-0292-5069)
- Elizabeth Huaroc Moquillaza
- Kilian Weiss
- Lisa Steinhelfer
- Rickmer Braren
Institutions
- TUM Klinikum (DE)
- Centre d'Imagerie BioMedicale (CH)
- Philips (Germany) (DE)
- École Polytechnique Fédérale de Lausanne (CH)
- Technical University of Munich (DE)
Publication Details
- Journal
- European Radiology Experimental
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1186/s41747-026-00689-z
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00