Comparison of [18F]PFPN and [18F]FDG PET in mucosal melanoma: diagnostic performance, staging impact, and correlation with molecular markers
[18F]PFPN PET outperforms [18F]FDG PET in lesion detection and clinical staging in mucosal melanoma, especially for liver and bone metastases. Its association with melanin differentiation markers may support its use in personalized imaging strategies.
Authors
- Xiaoli Lan
- T Liu
- Xi Zhang (ORCID: https://orcid.org/0000-0002-4638-3997)
- Xingyi Wang
- Zaijie Wu
- Cheng Tang
- Yongkang Gai
- W W Ruan
- Zhi Lin
- Fan Hu
Institutions
- Wuhan Union Hospital (CN)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1158/1078-0432.ccr-25-3953
- Primary Topic
- Cutaneous Melanoma Detection and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00