Correction for Xie et al., Click-constructed modular signal aptamer chimeras enable receptor-independent degradation of membrane proteins

The authors note that in the first paragraph under the subheading Enhanced Antitumor Efficacy of the SApt Platform in the Results, "The immunohistochemistry (IHC) analysis revealed weaker PTK7 signals and enhanced Ki67 staining in SApt#Sgc8-1.0treated tumor tissues, indicating a significant inhibition of tumor proliferation due to PTK7 depletion (Fig. 5F)" should instead appear as "The immunohistochemistry (IHC) analysis revealed weaker PTK7 signals and reduced Ki67 staining in SApt#Sgc8-1.0treated tumor tissues, indicating a significant inhibition of tumor proliferation due to PTK7 depletion (Fig. 5F )."Additionally, the authors note that Fig. 5F appeared incorrectly.Specifically, "during figure assembly, the correct image for the "Sgc8 (i.t.)" group within Fig. 5F was accidentally replaced with the image belonging to the "Sgc8 (i.v.)" group, resulting in duplication of the "Sgc8 (i.v.)" image in the "Sgc8 (i.t.)" panel."The corrected figure and its legend appear below.

Publication Details

Journal
Proceedings of the National Academy of Sciences
Published
2026-03-04
DOI
https://doi.org/10.1073/pnas.2604411123
Primary Topic
Protein Degradation and Inhibitors
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Correction for Xie et al., Click-constructed modular signal aptamer chimeras enable receptor-independent degradation of membrane proteins

Proceedings of the National Academy of Sciences
Protein Degradation and Inhibitors
article

Correction for Xie et al., Click-constructed modular signal aptamer chimeras enable receptor-independent degradation of membrane proteins

article en

Abstract

The authors note that in the first paragraph under the subheading Enhanced Antitumor Efficacy of the SApt Platform in the Results, "The immunohistochemistry (IHC) analysis revealed weaker PTK7 signals and enhanced Ki67 staining in SApt#Sgc8-1.0treated tumor tissues, indicating a significant inhibition of tumor proliferation due to PTK7 depletion (Fig. 5F)" should instead appear as "The immunohistochemistry (IHC) analysis revealed weaker PTK7 signals and reduced Ki67 staining in SApt#Sgc8-1.0treated tumor tissues, indicating a significant inhibition of tumor proliferation due to PTK7 depletion (Fig. 5F )."Additionally, the authors note that Fig. 5F appeared incorrectly.Specifically, "during figure assembly, the correct image for the "Sgc8 (i.t.)" group within Fig. 5F was accidentally replaced with the image belonging to the "Sgc8 (i.v.)" group, resulting in duplication of the "Sgc8 (i.v.)" image in the "Sgc8 (i.t.)" panel."The corrected figure and its legend appear below.

Proceedings of the National Academy of SciencesVol. 123(10)
Openalex Percentile: Top 35%
Protein Degradation and Inhibitors
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Correction for Xie et al., Click-constructed modular signal aptamer chimeras enable receptor-independent degradation of membrane proteins · Proceedings of the National Academy of Sciences (2026) | TGRS Research Map | TGRS