Correction for Xie et al., Click-constructed modular signal aptamer chimeras enable receptor-independent degradation of membrane proteins
The authors note that in the first paragraph under the subheading Enhanced Antitumor Efficacy of the SApt Platform in the Results, "The immunohistochemistry (IHC) analysis revealed weaker PTK7 signals and enhanced Ki67 staining in SApt#Sgc8-1.0treated tumor tissues, indicating a significant inhibition of tumor proliferation due to PTK7 depletion (Fig. 5F)" should instead appear as "The immunohistochemistry (IHC) analysis revealed weaker PTK7 signals and reduced Ki67 staining in SApt#Sgc8-1.0treated tumor tissues, indicating a significant inhibition of tumor proliferation due to PTK7 depletion (Fig. 5F )."Additionally, the authors note that Fig. 5F appeared incorrectly.Specifically, "during figure assembly, the correct image for the "Sgc8 (i.t.)" group within Fig. 5F was accidentally replaced with the image belonging to the "Sgc8 (i.v.)" group, resulting in duplication of the "Sgc8 (i.v.)" image in the "Sgc8 (i.t.)" panel."The corrected figure and its legend appear below.
Publication Details
- Journal
- Proceedings of the National Academy of Sciences
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1073/pnas.2604411123
- Primary Topic
- Protein Degradation and Inhibitors
- Type
- article
- Field-Weighted Citation Impact
- 0.00