The role of immune regulation in peripheral nerve regeneration: functions of inflammatory cells and cytokines
The integration of immunology and nerve regeneration research is opening new frontiers for treatment. Harnessing the regenerative potential of the immune system while restraining its detrimental effects-through approaches such as precision modulation of macrophage polarization, neutrophil extracellular trap regulation, and T cell-Schwann cell crosstalk targeting-offers encouraging prospects for overcoming the current challenges in peripheral nerve repair.
Authors
- Yan Zhang (ORCID: https://orcid.org/0000-0003-3744-6527)
- H.-Q. Zhang
- Xiangjun Meng
- Yun Su
- Wenguang Wu
- Min Nuo
- Haochen Jiang
Institutions
- Affiliated Zhongshan Hospital of Dalian University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-03-04
- DOI
- https://doi.org/10.3389/fphar.2026.1735833
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00