The microbial tryptophan metabolite indole acts on the gastrointestinal tract to improve glucose homeostasis in a mouse model of diabetes by enhancing GLP-1 secretion and L cell differentiation

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Publication Details

Journal
Diabetologia
Published
2026-03-04
DOI
https://doi.org/10.1007/s00125-026-06688-4
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00

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article

The microbial tryptophan metabolite indole acts on the gastrointestinal tract to improve glucose homeostasis in a mouse model of diabetes by enhancing GLP-1 secretion and L cell differentiation

Emile Otsubo, Daniela Pirri, Mariana Norton, Cecilia Dunsterville et al.
Diabetologia
Gut microbiota and health
article

The microbial tryptophan metabolite indole acts on the gastrointestinal tract to improve glucose homeostasis in a mouse model of diabetes by enhancing GLP-1 secretion and L cell differentiation

Emile Otsubo, Daniela Pirri, Mariana Norton, Cecilia Dunsterville, Brian Y.H. Lam, Bryn M. Owen, Shay Giles, Ben Jones, Gavin A. Bewick, Phyllis Phuah, Pei-En Chung, A G Irene Roberts, Aylin Carla Hanyaloglu, Sofia Aleksashina, Kevin G Murphy, Fiona M. Gribble, Rafal Karwowski, Frank Reimann, Leah Meyer
article en

Abstract

No abstract available for this paper.
Diabetologia
King's College London (GB), Hammersmith Hospital (GB), Wellcome/MRC Institute of Metabolic Science (GB), Imperial College London (GB)
Eli Lilly and Company, Wellcome Trust, Cancer Research UK, National Institute for Health and Care Research, Diabetes UK, Imperial College London, Medical Research Council, Biotechnology and Biological Sciences Research Council, Cancer Research UK Cambridge Institute, University of Cambridge
Zero hunger
Openalex Percentile: Top 35%
Gut microbiota and health
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