Integrated transcriptomic, protein, and MicroRNA profiling reveals a conserved pyroptosis-related molecular signature across breast cancer subtypes
This integrative analysis identifies a conserved pyroptosis-related molecular signature that deepens understanding of inflammatory programmed cell death in breast cancer and highlights interconnected pathways with diagnostic, prognostic, and therapeutic relevance.
Authors
- nikola zmarzły
- Kacper Boroń (ORCID: https://orcid.org/0000-0001-8207-5548)
- Martyna Stefaniak (ORCID: https://orcid.org/0000-0002-8036-8379)
- Paweł Ordon (ORCID: https://orcid.org/0000-0001-6163-104X)
- Beniamin Oskar Grabarek (ORCID: https://orcid.org/0000-0003-1633-7145)
- Grzegorz Wyrobiec (ORCID: https://orcid.org/0000-0002-4969-8636)
- Michalina Wróbel
- Dariusz Boroń (ORCID: https://orcid.org/0000-0002-2691-5829)
- Zbigniew Wróbel (ORCID: https://orcid.org/0000-0002-9609-7067)
- Agata Panfil
- Tomasz Sirek
- Piotr Wyrobiec
- Agata Sirek
- Piotr Ossowski
Institutions
- Real Academia Española (ES)
- Memorial Hospital of South Bend (US)
- Medical University of Silesia (PL)
- Wojewódzki Szpital Specjalistyczny nr 4 w Bytomiu (PL)
- Instytut Medycyny Wsi im. Witolda Chodźki (PL)
- Institute for Female Pelvic Medicine and Reconstructive Surgery (US)
- Andrzej Frycz Modrzewski Krakow University (PL)
- Collegium Medicum in Bydgoszcz (PL)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2026-03-04
- DOI
- https://doi.org/10.3389/fmolb.2026.1759944
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00