A novel approach to endophytic renal mass: Percutaneous indocyanine green injection for fluorescence-guided robot-assisted renal Tumorectomy
We report a novel fluorescence-guided approach for robot-assisted partial nephrectomy in a completely endophytic renal tumor. A 73-year-old woman with a 3-cm entirely endophytic left renal mass underwent ultrasound-guided percutaneous intratumoral indocyanine green injection after failure of selective arterial embolization. Near-infrared fluorescence imaging allowed accurate intraoperative localization and complete tumor enucleation. Operative time was 125 minutes, with a warm ischemia time of 25 minutes. The postoperative course was uneventful, renal function was preserved, and histopathology confirmed renal oncocytoma. Percutaneous intratumoral indocyanine green injection represents a safe and effective alternative for fluorescence-guided nephron-sparing surgery in anatomically challenging endophytic renal tumors.
Authors
- Giovanni Battista Di Pierro (ORCID: https://orcid.org/0000-0003-2321-0548)
- Bruno Bucca (ORCID: https://orcid.org/0000-0003-1321-4211)
- Valerio Santarelli (ORCID: https://orcid.org/0009-0009-9689-438X)
- Ivan Di Giulio
- Giovanni Di Lascio (ORCID: https://orcid.org/0000-0003-2925-6934)
- Michele Di Dio (ORCID: https://orcid.org/0000-0002-3227-5573)
- Carlo Maria Scornajenghi (ORCID: https://orcid.org/0000-0001-7600-7434)
- L.M. Gobbi
- Pier Giorgio Nardis
- Giorgio Franco
- Alessandro Sciarra
- Francesco Del Giudice
Institutions
- Policlinico Umberto I (IT)
- Ospedale Annunziata di Cosenza (IT)
Publication Details
- Journal
- Urology Case Reports
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1016/j.eucr.2026.103398
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00