Improvements in Time-Sensitive Stroke Care and Alteplase Administration: The Iranian Comprehensive Code Stroke Management Program (ICSM Phase III)

Implementing the updated protocol was associated with significant reductions in critical time intervals and a near-tripling of the intravenous alteplase administration rate in the intervention group. National evaluation should include long-term functional outcomes to confirm effectiveness and establish its value as a model.

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Publication Details

Journal
Stroke
Published
2026-03-04
DOI
https://doi.org/10.1161/strokeaha.125.053785
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Improvements in Time-Sensitive Stroke Care and Alteplase Administration: The Iranian Comprehensive Code Stroke Management Program (ICSM Phase III)

Nahid Dehghan Nayeri, Shahin Shifteh, Zoya Hadinezhad, Soraya Khafri et al.
Stroke
Acute Ischemic Stroke Management
article

Improvements in Time-Sensitive Stroke Care and Alteplase Administration: The Iranian Comprehensive Code Stroke Management Program (ICSM Phase III)

Nahid Dehghan Nayeri, Shahin Shifteh, Zoya Hadinezhad, Soraya Khafri, Fatemeh Bahramnezhad, Shayan Alijanpour
article en

Abstract

Implementing the updated protocol was associated with significant reductions in critical time intervals and a near-tripling of the intravenous alteplase administration rate in the intervention group. National evaluation should include long-term functional outcomes to confirm effectiveness and establish its value as a model.

Stroke
Iran University of Medical Sciences (IR), Imam Khomeini Hospital (IR), Pacific Heart Institute (US), Babol University of Medical Sciences (IR), Mazandaran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 36%
Acute Ischemic Stroke Management
DOISourceOpenAlex
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