Efficacy of NAs in combination with Peg-IFN for functional cure in patients with CHB: a meta-analysis of RCTs
Compared with NAs therapy, Peg-IFN combined with NAs therapy significantly improves functional cure rate. However, combination therapy shows no additional advantage over Peg-IFN monotherapy in achieving functional cure. The Peg-IFN monotherapy group has a higher incidence of ALT flares than the combination therapy group.
Authors
- Xinxin Li
- Yaqin Zhang
- Linmei Yao (ORCID: https://orcid.org/0000-0003-0442-7143)
- Xie Yy
- Shiyu Wang (ORCID: https://orcid.org/0000-0001-8851-1697)
- Ziyu Zhang (ORCID: https://orcid.org/0000-0003-2495-4880)
- Weihua Cao
- Wen Deng
- Xin Wei
- Minghui Li
Institutions
- King University (US)
- Capital Medical University (CN)
- Biology of Infection (FR)
- Beijing Ditan Hospital (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1080/07853890.2026.2636319
- Primary Topic
- Cancer Treatment and Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 0.00