Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury
Cur protects against PCABI by activating the Nrf2-PINK1 axis, enhancing mitophagy and suppressing ferroptosis, highlighting its therapeutic potential after CA.
Authors
- Jihong Xing (ORCID: https://orcid.org/0000-0002-6472-9517)
- Shurui Ren
- Zheng Li (26302)
- Qiang Zheng
- Wanling Xu
Institutions
- University of Electronic Science and Technology of China (CN)
- Jilin University (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2026-03-04
- DOI
- https://doi.org/10.1016/j.phymed.2026.158035
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00