Revision Lumbar Fusion Patients Exhibit Higher Long-Term Opioid and Gabapentinoid Needs Despite Similar Early Postoperative Use

Revision lumbar fusion patients demonstrate a greater pre- and postoperative opioid burden, and a greater postoperative gabapentinoid burden. Multivariable analysis confirms revision status as an independent risk factor of greater long-term MME use, beginning at 1 year. Together these findings suggest a complex, possibly neuropathic pain phenotype in revision patients, underscoring the need for tailored perioperative counseling and consistent long-term, multidisciplinary pain management.

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Publication Details

Journal
Spine
Published
2026-03-02
DOI
https://doi.org/10.1097/brs.0000000000005678
Primary Topic
Opioid Use Disorder Treatment
Type
article
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article

Revision Lumbar Fusion Patients Exhibit Higher Long-Term Opioid and Gabapentinoid Needs Despite Similar Early Postoperative Use

Nicholas B. Pohl, Gregorio Baek, Chloe Herczeg, Matthew Sherman et al.
Spine
Opioid Use Disorder Treatment
article

Revision Lumbar Fusion Patients Exhibit Higher Long-Term Opioid and Gabapentinoid Needs Despite Similar Early Postoperative Use

Nicholas B. Pohl, Gregorio Baek, Chloe Herczeg, Matthew Sherman, Rachel Huang, Anastasia Kaffenes, Jarod Olson, Joshua Mathew, Robert J. Oris, Marco Goldberg, Yasmine Eichbaum, Joydeep Baidya, Alan S. Hilibrand, Jonathan Dalton, Gregory D. Schroeder, Alexander R. Vaccaro, Nick DeMario, Morgan Hitchner, Christopher K. Kepler, Mitchell Ng, Thomas Cha, Samuel Duggan, Yulia Lee
article en

Abstract

Revision lumbar fusion patients demonstrate a greater pre- and postoperative opioid burden, and a greater postoperative gabapentinoid burden. Multivariable analysis confirms revision status as an independent risk factor of greater long-term MME use, beginning at 1 year. Together these findings suggest a complex, possibly neuropathic pain phenotype in revision patients, underscoring the need for tailored perioperative counseling and consistent long-term, multidisciplinary pain management.

Spine
National Medical Products Administration (CN), Thomas Jefferson University Hospital (US), Foundation for Human Potential (US), Ta Solutions (China) (CN), Rothman Institute (US), National Patient Safety Foundation (US)
Openalex Percentile: Top 39%
Opioid Use Disorder Treatment
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Revision Lumbar Fusion Patients Exhibit Higher Long-Term Opioid and Gabapentinoid Needs Despite Similar Early Postoperative Use — Nicholas B. Pohl, Gregorio Baek, et al. · Spine (2026) | TGRS Research Map | TGRS