Elucidating the <i>in vivo</i> fate of pharmaceutical excipient sodium carboxymethylcellulose in rats using UHPLC- Q TRAP MS/MS and UHPLC- Q TOF MS/MS approach
The findings provide complete description of sodium carboxymethylcellulose <i>in vivo</i> fate, establishing a novel framework that facilitates the extensive utilization of this pharmaceutical excipient in the process of drug formulation development.
Authors
- Kunqian Mu
- Guo Yin
- Na Yang (ORCID: https://orcid.org/0000-0002-5286-7656)
- Xiaowei Wang (ORCID: https://orcid.org/0000-0002-7479-8858)
- Aixian Liang
- Jingjing Liu
- Ran Liu
Institutions
- Shenyang Pharmaceutical University (CN)
- Shenyang Medical College (CN)
- Biotech Park (IN)
- Shenzhen Institute for Drug Control (CN)
Publication Details
- Journal
- Bioanalysis
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1080/17576180.2026.2621015
- Primary Topic
- Analytical Methods in Pharmaceuticals
- Type
- article
- Field-Weighted Citation Impact
- 0.00