A bioinformatics approach to identify potential biomarkers of high-grade ovarian cancer
The identification of these hub genes and pathways may represent an important step forward in our understanding of HGOC. While down-regulated genes may also hold biological significance, their analysis was beyond the scope of this study and warrants future investigation. Further experimental validation is needed to confirm the roles of the identified genes in disease pathogenesis and their potential as biomarkers and therapeutic targets.
Authors
- Murat İşbilen (ORCID: https://orcid.org/0000-0001-9968-5211)
- Güldal İnal Gültekin (ORCID: https://orcid.org/0000-0002-8313-6119)
- Deryanaz Billur (ORCID: https://orcid.org/0000-0002-6079-8224)
- Özlem Timirci Kahraman (ORCID: https://orcid.org/0000-0002-3690-0268)
- Saliha Durmuş
- Turgay İşbir (ORCID: https://orcid.org/0000-0002-7350-6032)
- Esin Bayralı Ülker
- İlhan Yaylım
- Tunahan Çakır
Institutions
- Yeditepe University (TR)
- Gebze Technical University (TR)
- Istanbul Aydın University (TR)
- HUN-REN Institute of Experimental Medicine (HU)
- Istanbul University (TR)
- Okan University (TR)
Publication Details
- Journal
- Journal of the Turkish-German Gynecological Association
- Published
- 2026-03-03
- DOI
- https://doi.org/10.4274/jtgga.galenos.2025.2025-1-1
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00