Early-life immunological and microbial differences between East African and North European children
These results highlight the early emergence of differences in the immune system and gut microbiota between children living in extremities of the microbial exposure gradient. These differences add to the existing knowledge of possible factors contributing to increasing prevalence of chronic inflammatory diseases in African societies shifting towards more Westernized lifestyle.
Authors
- Fan Yue-Mei
- Kalle Kurppa
- Noora Nurminen (ORCID: https://orcid.org/0000-0002-6798-7677)
- Olli H. Laitinen (ORCID: https://orcid.org/0000-0002-3751-9952)
- Emma Kortekangas (ORCID: https://orcid.org/0000-0003-2568-1941)
- Aki Sinkkonen
- Sami Oikarinen
- Ulla Ashorn
- Per Ashorn
- Kirsi-Maarit Lehto
- Lotta Hallamaa
- Riitta Veijola
- Jorma Toppari
- Heikki Hyöty
- Mikael Knip
- Johanna Lempainen
- Kenneth Maleta
- Jake Lin
Institutions
- Åbo Akademi University (FI)
- University of Helsinki (FI)
- Tampere University of Applied Sciences (FI)
- University of Turku (FI)
- Tampere University (FI)
- Seinäjoki University of Applied Sciences (FI)
- Turku Centre for Computer Science (FI)
- Oulu University Hospital (FI)
- Kamuzu Central Hospital (MW)
- Turku University Hospital (FI)
- Natural Resources Institute Finland (FI)
- Tampere University Hospital (FI)
- Tampere University (FI)
- Fimlab (Finland) (FI)
- Kamuzu University of Health Sciences (MW)
Publication Details
- Journal
- Communications Medicine
- Published
- 2026-03-03
- DOI
- https://doi.org/10.1038/s43856-026-01482-0
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Tampereen Tuberkuloosisäätiö
- Business Finland
- Faculty of Medicine and Health, University of Sydney