Maternal prenatal stress is associated with altered placental microstructure in low-risk pregnancies and pregnancies with Congenital Heart Disease
Maternal stress and placental MRI data acquired in pregnancies with and without CHDMaternal trait anxiety is associated with increased placental diffusivityMaternal state anxiety and depressive symptoms are higher in fetal CHDState anxiety and depressive symptoms not associated with placental MRI measuresCHD did not moderate relationships between placental MRI measures and stress.
Authors
- Kuberan Pushparajah (ORCID: https://orcid.org/0000-0003-1541-1155)
- Jordina Aviles Verdera (ORCID: https://orcid.org/0009-0007-7575-4244)
- Jana Hutter
- Daniel Cromb
- Serena J Counsell
- Mary A Rutherford
- Sarah Ahmad Javed
- Alexandra F Bonthrone
Institutions
- Leibniz University Hannover (DE)
- King's College London (GB)
- Evelina London Children's Healthcare (GB)
Publication Details
- Journal
- medRxiv
- Published
- 2026-03-03
- DOI
- https://doi.org/10.64898/2026.03.02.26347408
- Primary Topic
- Maternal Mental Health During Pregnancy and Postpartum
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research
- King's College London
- National Institutes of Health
- Medical Research Council
- Engineering and Physical Sciences Research Council
- Centre For Medical Engineering, King’s College London