Integrative genomic and immune landscape analysis of intimal sarcomas for emerging therapeutic targets and immunotherapy strategies

Our findings provided basic evidence for immunotherapy efficacy in intimal sarcomas and identified potential molecular targets. Further studies involving larger case series are required to validate these results.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-03-03
DOI
https://doi.org/10.3389/fimmu.2026.1723978
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Integrative genomic and immune landscape analysis of intimal sarcomas for emerging therapeutic targets and immunotherapy strategies

Alice Frazão Costa, Gianluca Folesani, Maria Concetta Nigro, Maria Abbondanza Pantaleo et al.
Frontiers in Immunology
Sarcoma Diagnosis and Treatment
article

Integrative genomic and immune landscape analysis of intimal sarcomas for emerging therapeutic targets and immunotherapy strategies

Alice Frazão Costa, Gianluca Folesani, Maria Concetta Nigro, Maria Abbondanza Pantaleo, Luisa Di Sciascio, Luca Bergamaschi, Ilenia Motta, Chiara Baldovini, Livia Gozzellino, Margherita Nannini, Francesco Angeli, Carmine Pizzi, Luigi Lovato, Barbara Corti, Gianandrea Pasquinelli, Davide Pacini, Annalisa Astolfi
article en

Abstract

Our findings provided basic evidence for immunotherapy efficacy in intimal sarcomas and identified potential molecular targets. Further studies involving larger case series are required to validate these results.

Frontiers in ImmunologyVol. 17
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola (IT), Azienda USL di Bologna (IT), Ospedale G.B. Morgagni - L.Pierantoni (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), University of Bologna (IT)
European Commission
Good health and well-being
Openalex Percentile: Top 35%
Sarcoma Diagnosis and Treatment
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Integrative genomic and immune landscape analysis of intimal sarcomas for emerging therapeutic targets and immunotherapy strategies — Alice Frazão Costa, Gianluca Folesani, et al. · Frontiers in Immunology (2026) | TGRS Research Map | TGRS