Comparison of Atheroma Burden Changes Using Conventional vs. End-Diastolic Intravascular Ultrasound Segmentation ― Post Hoc Analysis of the PACMAN-AMI Study ―
ED- and 1-mm-based analyses demonstrated comparable treatment effects of alirocumab on plaque regression in PACMAN-AMI. These findings support the use of the less time-consuming 1-mm segmentation method in serial IVUS studies.
Authors
- Jonas Häner (ORCID: https://orcid.org/0000-0002-1420-8967)
- Nicole Ng (ORCID: https://orcid.org/0000-0001-6614-4427)
- Nathan Angelo Lecaros Yap (ORCID: https://orcid.org/0000-0001-6294-5796)
- Tatsuhiko Otsuka (ORCID: https://orcid.org/0000-0001-7737-0374)
- Christos V. Bourantas (ORCID: https://orcid.org/0000-0001-5319-1064)
- Ernest Spitzer (ORCID: https://orcid.org/0000-0003-2371-5431)
- Thomas Engstrøm
- Sylvain Losdat (ORCID: https://orcid.org/0000-0001-7673-4877)
- Yasushi Ueki
- R Kakizaki
- David Spirk
- I H Tanboga
- Anthony Mathur
- Jouke Dijkstra
- Lorenz Räber
- Andreas Baumbach
Institutions
- University of Bern (CH)
- Bern University of Applied Sciences (CH)
- Queen Mary University of London (GB)
- Barts Health NHS Trust (GB)
- Leiden University Medical Center (NL)
- University Hospital of Bern (CH)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- İstanbul Nişantaşı Üniversitesi (TR)
- William Harvey Research Institute (GB)
- Cardialysis (Netherlands) (NL)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Circulation Journal
- Published
- 2026-03-03
- DOI
- https://doi.org/10.1253/circj.cj-25-0590
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00