Network localization of functional and structural correlates of apathy in Parkinson’s disease

Brain functional and structural correlates of apathy in PD converge on distributed networks involving the VAN, FPN, and subcortical circuits. Our network localization approach offers a unifying neurobiological framework for apathy in PD, potentially reconciling previous inconsistencies and informing the development of network-targeted interventions.

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Publication Details

Journal
Frontiers in Systems Neuroscience
Published
2026-03-03
DOI
https://doi.org/10.3389/fnsys.2026.1724421
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Network localization of functional and structural correlates of apathy in Parkinson’s disease

Si-Yu Gu, Yuanying Song, Hai-Hua Sun, Hucheng Yang et al.
Frontiers in Systems Neuroscience
Functional Brain Connectivity Studies
article

Network localization of functional and structural correlates of apathy in Parkinson’s disease

Si-Yu Gu, Yuanying Song, Hai-Hua Sun, Hucheng Yang, Ping-Lei Pan, Feng-Mei Zhang, Zhen-Yu Dai
article en

Abstract

Brain functional and structural correlates of apathy in PD converge on distributed networks involving the VAN, FPN, and subcortical circuits. Our network localization approach offers a unifying neurobiological framework for apathy in PD, potentially reconciling previous inconsistencies and informing the development of network-targeted interventions.

Frontiers in Systems NeuroscienceVol. 20
Yancheng Third People's Hospital (CN), Weihai Maternal and Child Health Hospital (CN)
Jiangsu Commission of Health, Anhui Medical University, Nantong University, Bijzonder Onderzoeksfonds UGent
Openalex Percentile: Top 39%
Functional Brain Connectivity Studies
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