Splenic B‐Cell Lymphoma/Leukemia With <scp> <i>TCL1</i> </scp> Gene Rearrangement
The identification of IGH::TCL1 fusion in these two cases of splenic B-cell lymphoma/leukemia suggests that TCL1 gene rearrangements can occur in B-cell lymphoma/leukemia and should not be considered exclusive to T-cell prolymphocytic leukemia. Accurate diagnosis of splenic B-cell lymphoma/leukemia with TCL1 rearrangement requires evaluation of morphologic and immunophenotypic features and genetic assessment of TCL1.
Authors
- Shimin Hu
- Zhihong Hu
- L Jeffrey Medeiros
- Guilin Tang
- Xin Wang
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Albany Medical Center Hospital (US)
Publication Details
- Journal
- International Journal of Laboratory Hematology
- Published
- 2026-03-03
- DOI
- https://doi.org/10.1111/ijlh.70082
- Primary Topic
- Chronic Lymphocytic Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00